Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells?

@article{Sobern2008SignalingVP,
  title={Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells?},
  author={Mario Sober{\'o}n and Sarjeet S. Gill and Alejandra Bravo},
  journal={Cellular and Molecular Life Sciences},
  year={2008},
  volume={66},
  pages={1337-1349}
}
Abstract.Cry proteins, produced by Bacillus thuringiensis (Bt), are widely used for the control of insect pests in agriculture as spray products or expressed in transgenic crops, such as maize and cotton. Little was known regarding the mechanism of action of these toxins when the first commercial Bt product was introduced fifty years ago. However, research on the mechanism of action over the last two decades has enhanced our knowledge of toxin interaction with membrane receptors and their… 

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