Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.

Abstract

Bone remodeling is regulated by various neuronal inputs, including sympathetic tone, which is known to inhibit bone mass accrual. This aspect of sympathetic nervous system function raises the prospect that the other arm of the autonomic nervous system, the parasympathetic nervous system, may also affect bone remodeling. Here, we use various mutant mouse… (More)
DOI: 10.1016/j.cmet.2010.01.005

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@article{Shi2010SignalingTT, title={Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.}, author={Y M Shi and Franck Oury and Vijay K Yadav and Juergen Wess and X. Sherry Liu and X. Edward Guo and Monzur Murshed and Gerard Karsenty}, journal={Cell metabolism}, year={2010}, volume={11 3}, pages={231-8} }