Signaling system in Porphyromonas gingivalis based on a LuxS protein.

  title={Signaling system in Porphyromonas gingivalis based on a LuxS protein.},
  author={Whasun Oh Chung and Youngjin Park and Richard J Lamont and Roderick McNab and Bruno Barbieri and Donald R Demuth},
  journal={Journal of bacteriology},
  volume={183 13},
The luxS gene of quorum-sensing Vibrio harveyi is required for type 2 autoinducer production. We identified a Porphyromonas gingivalis open reading frame encoding a predicted peptide of 161 aa that shares 29% identity with the amino acid sequence of the LuxS protein of V. harveyi. Conditioned medium from a late-log-phase P. gingivalis culture induced the luciferase operon of V. harveyi, but that from a luxS insertional mutant did not. In P. gingivalis, the expression of luxS mRNA was… CONTINUE READING


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