Signaling pathways and effector mechanisms pre-programmed cell death.

  title={Signaling pathways and effector mechanisms pre-programmed cell death.},
  author={Neal B. Blatt and Gary D Glick},
  journal={Bioorganic & medicinal chemistry},
  volume={9 6},
Apoptosis is a complex biochemical process that involves all aspects of the cell from the plasma membrane to the nucleus. Apoptosis stimuli are mediated by many different cellular processes including protein synthesis and degradation, the alteration in protein phosphorylation states, the activation of lipid second messenger systems, and disruption of normal mitochondrial function. Despite this diversity in signal transduction, all apoptotic pathways are believed to converge ultimately with the… CONTINUE READING
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