Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis.

@article{Sun2015SignalingPO,
  title={Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis.},
  author={Yu Sun and Wen-Zhou Liu and Tao Liu and Xu Feng and Nuo Yang and Hua-Fu Zhou},
  journal={Journal of receptor and signal transduction research},
  year={2015},
  volume={35 6},
  pages={600-4}
}
The generic mitogen-activated protein kinases (MAPK) signaling pathway is shared by four distinct cascades, including the extracellular signal-related kinases (ERK1/2), Jun amino-terminal kinases (JNK1/2/3), p38-MAPK and ERK5. Mitogen-activated protein kinases/extracellular signal-regulated kinase (MAPK/ERK) pathway is reported to be associated with the cell proliferation, differentiation, migration, senescence and apoptosis. The literatures were searched extensively and this review was… CONTINUE READING