Signaling of interleukin-17 family cytokines in immunity and inflammation.

Abstract

IL-17 cytokine family, though still young since discovery, has recently emerged as critical players in immunity and inflammatory diseases. The prototype cytokine, IL-17A, plays essential roles in promoting inflammation and host defense. IL-17RA, a member of the IL-17 receptor family, forms a complex with another member, IL-17RC, to mediate effective… (More)
DOI: 10.1016/j.cellsig.2010.11.022

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