Signaling mechanisms regulating B-lymphocyte activation and tolerance


It is becoming more and more accepted that, in addition to producing autoantibodies, B lymphocytes have other important functions that influence the development of autoimmunity. For example, autoreactive B cells are able to produce inflammatory cytokines and activate pathogenic T cells. B lymphocytes can react to extracellular signals with a range of… (More)
DOI: 10.1007/s00109-015-1252-8


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