Signaling mechanisms in progesterone-neurotransmitter interactions.

Abstract

Ovarian steroid hormones, estradiol and progesterone, modulate neuroendocrine functions in the CNS resulting in alterations in physiology in female mammals. Classical model of steroid hormone action assumes that these neural effects are predominantly mediated via their intracellular receptors functioning as "ligand-dependent" transcription factors in the… (More)

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