Signaling in muscle atrophy and hypertrophy.

  title={Signaling in muscle atrophy and hypertrophy.},
  author={Marco Sandri},
Muscle performance is influenced by turnover of contractile proteins. Production of new myofibrils and degradation of existing proteins is a delicate balance, which, depending on the condition, can promote muscle growth or loss. Protein synthesis and protein degradation are coordinately regulated by pathways that are influenced by mechanical stress, physical activity, availability of nutrients, and growth factors. Understanding the signaling that regulates muscle mass may provide potential… CONTINUE READING
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