Signaling in Radiation-Induced Bystander Effects Mediated − B κ Mitochondrial Function and Nuclear Factor-Updated

@inproceedings{Zhou2008SignalingIR,
  title={Signaling in Radiation-Induced Bystander Effects Mediated − B κ Mitochondrial Function and Nuclear Factor-Updated},
  author={Hongning Zhou and Vladimir N. Ivanov and Yu-chin Lien and Mercy M. Davidson and Tom K. Hei},
  year={2008}
}
Although radiation-induced bystander effects have been well described over the past decade, the mechanisms of the signaling processes involved in the bystander phenomenon remain unclear. In the present study, using the Columbia University charged particle microbeam, we found that mitochondrial DNA–depleted human skin fibroblasts (R) showed a higher bystander mutagenic response in confluent monolayers when a fraction of the same population were irradiated with lethal doses compared with their… CONTINUE READING

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