Signaling from cAMP/PKA to MAPK and synaptic plasticity

Abstract

The facilitation of hippocampus-based, long-lasting synaptic plasticity, which is frequently investigated in model systems such as long-term potentiation (LTP) and in learning paradigms such as the Morris water maze, is associated with several cellular key events: Ca2+ influx through the n-methyl-d-aspartate (NMDA) receptor, generation of cyclic AMP (cAMP… (More)
DOI: 10.1385/MN:27:1:99

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