Signaling for Synergistic Activation of Natural Killer Cells

@inproceedings{Kwon2012SignalingFS,
  title={Signaling for Synergistic Activation of Natural Killer Cells},
  author={Hyung-Joon Kwon and Hun Sik Kim},
  booktitle={Immune network},
  year={2012}
}
Natural killer (NK) cells play a pivotal role in early surveillance against virus infection and cellular transformation, and are also implicated in the control of inflammatory response through their effector functions of direct lysis of target cells and cytokine secretion. NK cell activation toward target cell is determined by the net balance of signals transmitted from diverse activating and inhibitory receptors. A distinct feature of NK cell activation is that stimulation of resting NK cells… CONTINUE READING

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