Signaling by synaptogenic molecules.

  title={Signaling by synaptogenic molecules.},
  author={Thomas Biederer and Massimiliano Stagi},
  journal={Current opinion in neurobiology},
  volume={18 3},
Multiple signaling pathways initiate and specify the formation of synapses in the central nervous system. General principles that organize nascent synapses have emerged from the studies in multiple model organisms. These include the synapse-organizing roles of dedicated synaptic adhesion molecules, synaptic signaling following receptor-ligand interactions, and the regulation of synapse formation by secreted molecules. Intracellularly, a range of effectors subsequently regulates signaling steps… CONTINUE READING