Signaling by reactive oxygen species in the nervous system

  title={Signaling by reactive oxygen species in the nervous system},
  author={Pamela Maher and Dominic Schubert},
  journal={Cellular and Molecular Life Sciences CMLS},
Free radicals and reactive oxygen species (ROS) are involved in a variety of different cellular processes ranging from apoptosis and necrosis to cell proliferation and carcinogenesis. Cells contain multiple sites for ROS production and a few mechanisms for their degradation. Which of these sites is activated by a given stimulus may play a role in dictating the subsequent downstream effects of the ROS generated on cellular function. Even when the ultimate outcome is similar, such as when ROS… CONTINUE READING


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Cytokines and JAKSTAT signaling

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