Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes.

  title={Signaling by environmental polycyclic aromatic hydrocarbons in human lymphocytes.},
  author={Scott W. Burchiel and Michael I. Luster},
  journal={Clinical immunology},
  volume={98 1},
During the past decade there has been significant progress made in understanding how environmental agents, drugs, certain chemicals present in the diet, and occupational agents affect the immune system of animals and humans. Polycyclic aromatic hydrocarbons (PAHs) are an important class of environmentally prevalent xenobiotics that exert complex effects on the immune system. These agents, typified by benzo(a)pyrene (BaP), have been shown to alter antigen and mitogen receptor signaling pathways… CONTINUE READING


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