Signaling and regulation of the platelet glycoprotein Ib–IX–V complex

@article{Du2007SignalingAR,
  title={Signaling and regulation of the platelet glycoprotein Ib–IX–V complex},
  author={Xiaoping Du},
  journal={Current Opinion in Hematology},
  year={2007},
  volume={14},
  pages={262–269}
}
  • Xiaoping Du
  • Published 2007
  • Biology, Medicine
  • Current Opinion in Hematology
Purpose of reviewThe platelet adhesion receptor, the glycoprotein Ib–IX–V complex, not only mediates platelet adhesion but also transmits signals leading to platelet activation, aggregation and secretion. Significant progress has been made recently on the signaling pathways and regulatory mechanisms involving glycoprotein Ib–IX–V function. Recent findingsThe interaction of glycoprotein Ib–IX–V with its ligand, von Willebrand factor, is dually controlled by von Willebrand factor conformation and… Expand
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  • S. Li, Z. Wang, +5 authors K. Dai
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  • 2010
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