Signaling and Gene Regulatory Networks Governing Definitive Endoderm Derivation From Pluripotent Stem Cells.

@article{Mohammadnia2016SignalingAG,
  title={Signaling and Gene Regulatory Networks Governing Definitive Endoderm Derivation From Pluripotent Stem Cells.},
  author={Abdulshakour Mohammadnia and Moein Yaqubi and Farzaneh Pourasgari and Eric Neely and Hossein Fallahi and Mohammad Massumi},
  journal={Journal of cellular physiology},
  year={2016},
  volume={231 9},
  pages={
          1994-2006
        }
}
The generation of definitive endoderm (DE) from pluripotent stem cells (PSCs) is a fundamental stage in the formation of highly organized visceral organs, such as the liver and pancreas. Currently, there is a need for a comprehensive study that illustrates the involvement of different signaling pathways and their interactions in the derivation of DE cells… CONTINUE READING