Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer

@inproceedings{Yan2013SignalingNO,
  title={Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer},
  author={Bin Yan and Robert Vander Broek and Anthony D. Saleh and Arpita I. Mehta and Carter Van Waes and Zhong Chen},
  booktitle={Journal of carcinogenesis & mutagenesis},
  year={2013}
}
Head and neck squamous cell carcinoma (HNSCC) arises from the upper aerodigestive tract and is the six most common cancers worldwide. HNSCC is associated with high morbidity and mortality, as standard surgery, radiation, and chemotherapy can cause significant disfigurement and only provide 5-year survival rates of ~50-60%. The heterogeneity of HNSCC subsets… CONTINUE READING