Signal transduction of V1-vascular vasopressin receptors.

  title={Signal transduction of V1-vascular vasopressin receptors.},
  author={Marc Thibonnier},
  journal={Regulatory peptides},
  volume={38 1},
This review covers the recent developments gained in the exploration of V1-vascular vasopressin (AVP) receptors. We examine the different radioligands available for the pharmacological characterization of these receptors. The immediate transmembrane signaling of V1-vascular AVP receptors involves ligand-receptor complex formation, receptor lateral mobility and internalization, coupling to a Gq protein, activation of phospholipases A2, C and D, translocation and activation of protein kinase C… CONTINUE READING
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