Signal transduction mechanisms mediating secretion in goldfish gonadotropes and somatotropes.

@article{Chang2000SignalTM,
  title={Signal transduction mechanisms mediating secretion in goldfish gonadotropes and somatotropes.},
  author={John T. Chang and James D Johnson and Frederick van Goor and Calvin J H Wong and Warren K. Yunker and Aubrey D Uretsky and Devon Taylor and Richard M. Jobin and Anderson O L Wong and Jeffrey I. Goldberg},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2000},
  volume={78 3},
  pages={139-53}
}
The intracellular signal transduction mechanisms mediating maturational gonadotropin and somatotropin secretion in goldfish are reviewed. Several major signaling mechanisms, including changes in intracellular [Ca2+], arachidonic acid cascades, protein kinase C, cyclic AMP/protein kinase A, calmodulin, nitric oxide, and Na+/H+ antiport, are functional in both cell types. However, their relative importance in mediating basal secretion and neuroendocrine-factor-regulated hormone release differs… CONTINUE READING