Signal transduction in eclosion hormone-induced secretion of ecdysis-triggering hormone.

@article{Kingan2001SignalTI,
  title={Signal transduction in eclosion hormone-induced secretion of ecdysis-triggering hormone.},
  author={T G Kingan and Richard A Cardullo and Michael E Adams},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 27},
  pages={25136-42}
}
Inka cells of insect epitracheal glands (EGs) secrete preecdysis and ecdysis-triggering hormones (PETH and ETH) at the end of each developmental stage. Both peptides act in the central nervous system to evoke the ecdysis behavioral sequence, a stereotype behavior during which old cuticle is shed. Secretion of ETH is stimulated by a brain neuropeptide, eclosion hormone (EH). EH evokes accumulation of cGMP followed by release of ETH from Inka cells, and exogenous cGMP evokes secretion of ETH. The… CONTINUE READING