Signal transduction from bradykinin, angiotensin, adrenergic and muscarinic receptors to effector enzymes, including ADP-ribosyl cyclase.

@article{Higashida2001SignalTF,
  title={Signal transduction from bradykinin, angiotensin, adrenergic and muscarinic receptors to effector enzymes, including ADP-ribosyl cyclase.},
  author={Haruhiro Higashida and Shigeru Yokoyama and Naoto Hoshi and Minako Hashii and Anastasia Egorova and Zhongguo Zhong and Mami Noda and Mohammad Shahidullah and M Taketo and Rimma Knijnik and Yasuhisa Kimura and Honami Takahashi and Xuejun Chen and Yangchol Shin and Julie S Zhang},
  journal={Biological chemistry},
  year={2001},
  volume={382 1},
  pages={23-30}
}
Muscarinic acetylcholine receptors in NG108-15 neuroblastoma x glioma cells, and beta-adrenergic or angiotensin II receptors in cortical astrocytes and/or ventricular myocytes, utilize the direct signaling pathway to ADP-ribosyl cyclase within cell membranes to produce cyclic ADP-ribose (cADPR) from beta-NAD+. This signal cascade is analogous to the previously established transduction pathways from bradykinin receptors to phospholipase Cbeta and beta-adrenoceptors to adenylyl cyclase via G… CONTINUE READING
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