Signal transduction by MAP kinase cascades in budding yeast.

  title={Signal transduction by MAP kinase cascades in budding yeast.},
  author={Francesc Posas and Mutsuhiro Takekawa and Haruo Saito},
  journal={Current opinion in microbiology},
  volume={1 2},
Budding yeast contain at least four distinct MAPK (mitogen activated protein kinase) cascades that transduce a variety of intracellular signals: mating-pheromone response, pseudohyphal/invasive growth, cell wall integrity, and high osmolarity adaptation. Although each MAPK cascade contains a conserved set of three protein kinases, the upstream activation mechanisms for these cascades are diverse, including a trimeric G protein, monomeric small G proteins, and a prokaryotic-like two-component… CONTINUE READING