Signal transduction at fertilization: the Ca2+ release pathway in echinoderms and other invertebrate deuterostomes.

@article{Townley2006SignalTA,
  title={Signal transduction at fertilization: the Ca2+ release pathway in echinoderms and other invertebrate deuterostomes.},
  author={Ian K Townley and Michelle M Roux and Kathy R. Foltz},
  journal={Seminars in cell & developmental biology},
  year={2006},
  volume={17 2},
  pages={293-302}
}
Gamete interaction and fusion triggers a number of events that lead to egg activation and development of a new organism. A key event at fertilization is the rise in intracellular calcium. In deuterostomes, this calcium is released from the egg's endoplasmic reticulum and is necessary for proper activation. This article reviews recent data regarding how gamete interaction triggers the initial calcium release, focusing on the echinoderms (invertebrate deuterostomes) as model systems. In eggs of… CONTINUE READING