Signal transduction: An eye on organ development

@article{Epstein2003SignalTA,
  title={Signal transduction: An eye on organ development},
  author={Jonathan A. Epstein and Benjamin G Neel},
  journal={Nature},
  year={2003},
  volume={426},
  pages={238-239}
}
outside signals and transmit them into the nucleus have been so well scrutinized that one might think few surprises remain. But three papers in this issue show otherwise. During development, many of the signalling pathways that regulate organ formation are initiated by growth factors that bind to receptors on the cell surface. This triggers a cascade of events inside the cell that frequently involves the addition or removal of phosphate groups (phosphorylation or dephosphorylation, respectively… CONTINUE READING

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