Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone.

Abstract

GH plays a central role in controlling somatic growth, tissue regeneration, and intermediary metabolism in most vertebrate species through mechanisms dependent on the regulation of gene expression. Recent studies using transcript profiling have identified large cohorts of genes whose expression is induced by GH. Other results have demonstrated that signal… (More)

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@article{Ono2007SignalTA, title={Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: a mechanism for repression of gene expression by growth hormone.}, author={Mitsuru Ono and Dennis Joshua Chia and Roxana Merino-Martinez and Amilcar Flores-Morales and Terry G. Unterman and Peter Rotwein}, journal={Molecular endocrinology}, year={2007}, volume={21 6}, pages={1443-57} }