Signal-sequence induced conformational changes in the signal recognition particle

@inproceedings{Hainzl2015SignalsequenceIC,
  title={Signal-sequence induced conformational changes in the signal recognition particle},
  author={Tobias Hainzl and A. Elisabeth Sauer-Eriksson},
  booktitle={Nature communications},
  year={2015}
}
Co-translational protein targeting is an essential, evolutionarily conserved pathway for delivering nascent proteins to the proper cellular membrane. In this pathway, the signal recognition particle (SRP) first recognizes the N-terminal signal sequence of nascent proteins and subsequently interacts with the SRP receptor. For this, signal sequence binding in… CONTINUE READING