Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae.

@article{Bardwell1994SignalPA,
  title={Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae.},
  author={Lee Bardwell and Jeanette Gowen Cook and C J Inouye and J. Thorner},
  journal={Developmental biology},
  year={1994},
  volume={166 2},
  pages={363-79}
}
Extracellular signals can affect the rate of proliferation and the state of differentiation of eukaryotic cells. Signal transduction pathways have evolved to detect these signals at the plasma membrane, transmit them through the cytoplasm and into the nucleus, and thereby generate the appropriate changes in metabolism and transcription. Much attention has been focused recently on regulatory pathways of this sort that lead to activation of a family of protein kinases known as the mitogen- or… CONTINUE READING

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