Signal perception by the secretion stress-responsive CssRS two-component system in Bacillus subtilis.

@article{Noone2012SignalPB,
  title={Signal perception by the secretion stress-responsive CssRS two-component system in Bacillus subtilis.},
  author={David Noone and Eric Botella and Clodagh Butler and Annette Hansen and Inga Jende and Kevin M Devine},
  journal={Journal of bacteriology},
  year={2012},
  volume={194 7},
  pages={1800-14}
}
The CssRS two-component system responds to heat and secretion stresses in Bacillus subtilis by controlling expression of HtrA and HtrB chaperone-type proteases and positively autoregulating its own expression. Here we report on the features of the CssS extracellular loop domain that are involved in signal perception and on CssS subcellular localization. Individual regions of the CssS extracellular loop domain contribute differently to signal perception and activation. The conserved hydrophilic… CONTINUE READING
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