Signal maps for mass spectrometry-based comparative proteomics.

@article{Prakash2006SignalMF,
  title={Signal maps for mass spectrometry-based comparative proteomics.},
  author={Amol Prakash and Parag Mallick and Jeffrey R Whiteaker and Heidi Zhang and Amanda G. Paulovich and Mark R. Flory and Hookeun Lee and Ruedi Aebersold and Benno Schwikowski},
  journal={Molecular & cellular proteomics : MCP},
  year={2006},
  volume={5 3},
  pages={
          423-32
        }
}
Mass spectrometry-based proteomic experiments, in combination with liquid chromatography-based separation, can be used to compare complex biological samples across multiple conditions. These comparisons are usually performed on the level of protein lists generated from individual experiments. Unfortunately given the current technologies, these lists typically cover only a small fraction of the total protein content, making global comparisons extremely limited. Recently approaches have been… CONTINUE READING

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