• Corpus ID: 16993856

Signal Processing Overview of Optical Coherence Tomography Systems for Medical Imaging

  title={Signal Processing Overview of Optical Coherence Tomography Systems for Medical Imaging},
  author={S. H. Yun and Gary J. Tearney and Brett E. Bouma and B. Hyle Park and Woonggyu Jung and J. Stuart Nelson and Z. Chen},
Optical Coherence Tomography (OCT) is a new medical imaging modality with resolution in the μm range and depth of imaging in the mm range. OCT is based on the principle of low coherence interferometry. This modality has been applied to imaging in various biological applications including ophthalmology, gastroenterology, dentistry, cardiology, tumor margining, etc. OCT systems are signal processing intensive and well suited for embedded implementations using digital signal processors (DSP) and… 

Signal processing of Spectral Domain Optical Coherence Tomography

  • Y. RaoN. SarwadeR. Makkar
  • Physics
    2015 International Conference on Communication, Information & Computing Technology (ICCICT)
  • 2015
The basic principle, theory, types of OCT, signal processing steps and its applications in medical field are described and some of the results related to signal processing that were discussed from simulation using MATLAB and Lab VIEW are discussed.

Optical Coherence Tomography Systems and signal processing in SD-OCT

Optical Coherence Tomography (OCT) is a high speed image acquisition technique. It is used for high resolution cross-sectional imaging. It can acquire images of a biomedical objects in the scale of

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The aim is to develop the signal processing algorithm to achieve improved imaging depth in the spectral-domain OCT (SD-OCT), a growing non-invasive imaging technology capable of generating high-resolution cross-sectional images and high processing speed.

High resolution imaging system using spectral domain Optical Coherence Tomography using NIR source

Optical Coherence Tomography (OCT) is one of the recent technological development in the field of medicine. A noninvasive technique dependent on interference and back reflections of the signal is

FDOCT imaging processor for portable OCT systems with high imaging rate

: Frequency-domain optical coherence tomography (FDOCT) has been widely applied in medical image inspection. This paper presents an image formation processor capable of performing all FDOCT imaging


This research work discusses the basics of spectral domain OCT (SD-OCT), experimental setup, data acquisition and signal processing involved in OCT systems, and some of the results thus obtained have been discussed in the end.

A Review on Development of a High Resolution Imaging System at 635 nm and 840 nm

This Optical Coherence Tomography (OCT) is a non-invasive technology which is used in medical and nonmedical applications to produce high-resolution images. It provides the cross-sectional images of

A scalable approach to processing adaptive optics optical coherence tomography data from multiple sensors using multiple graphics processing units

A novel approach to processing AO-OCT data from the unique multi-camera optics system is tested on multiple graphics processing units (GPUs) in parallel with one, two, and four camera combinations, demonstrating a scalable, reusable, extensible method of computing AO -OCT output.

Efficient OCT Volume Reconstruction From Slitlamp Microscopes

A slitlamp-integrated OCT device, built with off-the-shelf components, which can generate high-quality volumetric images of the posterior eye segment and is an OCT device that can match current systems in clinical practice, at a significantly lower cost.

Hardware/Software Codesign for Portable Optical Coherence Tomography (OCT) Applications

  • Song-Nien TangChih-Yu HsiangSheng-Jie Huang
  • Computer Science
    2018 Joint 7th International Conference on Informatics, Electronics & Vision (ICIEV) and 2018 2nd International Conference on Imaging, Vision & Pattern Recognition (icIVPR)
  • 2018
This paper presents a hardware-software codesign scheme for the image formation of the Fourier-domain optical coherence tomography (FDOCT) system that could be developed based on a small-scale system, which lends support to the trend of portable FDOCT applications.



Real-time swept source optical coherence tomography imaging of the human airway using a microelectromechanical system endoscope and digital signal processor.

A real-time system with 20-kHz axial line speed, which was limited only by the swept laser scan rate, was implemented and in vivo 3-D imaging of the human airway was demonstrated.

Real-time in vivo color Doppler optical coherence tomography.

Issues of velocity sensitivity, imaging speed, and range of velocity measurement are discussed, as well as potential applications of real-time CDOCT.

Theory, developments and applications of optical coherence tomography

A number of different OCT techniques are discussed in some detail including time-domain, frequency- domain, full-field, quantum and Doppler OCT.

High speed spectral domain polarization sensitive optical coherence tomography of the human retina.

The system uses two spectrometers, one for each polarization channel, that operate in parallel at 20000 A-lines/s each and provides reflectivity, retardation, and cumulative optic axis orientation simultaneously.

Autofocus algorithm for dispersion correction in optical coherence tomography.

An autofocus algorithm is presented for estimating the delay line and material dispersion from OCT reflectance data, integrating a previously presented dispersion compensation algorithm to correct the data.

High-speed spectral-domain optical coherence tomography at 1.3 mum wavelength.

The results demonstrate the potential of 1.3 microm SD-OCT for high-speed and high-sensitivity imaging in patients and show similar penetration depths to those obtained with state-of-the-art time domain OCT despite the ten-fold higher image acquisition speed.

Polarization-sensitive spectral-domain optical coherence tomography using a single line scan camera.

A spectral-domain polarization-sensitive optical coherence tomography system that uses a spectrometer configuration with a single line scan camera and a Wollaston prism in the detection arm is presented and demonstrates variations in retinal thickness and double pass phase retardation per unit depth that were similar to data from the same volunteer taken with a time-domain polarized-sensitive system.

Polarization-sensitive complex Fourier domain optical coherence tomography for Jones matrix imaging of biological samples

A polarization-sensitive Fourier domain optical coherence tomography (PS-FD-OCT) system is demonstrated. This OCT system is based on a spectral interferometer, does not require mechanical axial

Sensitivity advantage of swept source and Fourier domain optical coherence tomography.

Results are presented which demonstrate the superior sensitivity of swept source (SS) and Fourier domain (FD) optical coherence tomography (OCT) techniques over the conventional time domain (TD) approach.

Enhanced optical coherence tomography imaging by multiple scan averaging

Improved retinal imaging enabled assignment of the OCT image to retinal anatomy particularly at the outer layer of the photoreceptors and the retinal pigment epithelium, both in the healthy eye and in pathology.