Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott–Aldrich Syndrome

Abstract

Over the last decades, research dedicated to the molecular and cellular mechanisms underlying primary immunodeficiencies (PID) has helped to understand the etiology of many of these diseases and to develop novel therapeutic approaches. Beyond these aspects, PID are also studied because they offer invaluable natural genetic tools to dissect the human immune… (More)
DOI: 10.3389/fimmu.2015.00047

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Cite this paper

@inproceedings{CottadeAlmeida2015SignalID, title={Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott–Aldrich Syndrome}, author={Vin{\'i}cius Cotta-de-Almeida and Lo{\"{i}c Dupr{\'e} and Delphine Guipouy and Zilton Farias Meira de Vasconcelos}, booktitle={Front. Immunol.}, year={2015} }