Signal Exchange through Extracellular Vesicles in Neuromuscular Junction Establishment and Maintenance: From Physiology to Pathology

@inproceedings{Maggio2019SignalET,
  title={Signal Exchange through Extracellular Vesicles in Neuromuscular Junction Establishment and Maintenance: From Physiology to Pathology},
  author={Serena Maggio and Paola Ceccaroli and Emanuela Polidori and Andrea Cioccoloni and Vilberto Stocchi and Michele Guescini},
  booktitle={International journal of molecular sciences},
  year={2019}
}
Neuromuscular junction (NMJ) formation involves morphological changes both in motor terminals and muscle membrane. The molecular mechanisms leading to NMJ formation and maintenance have not yet been fully elucidated. During the last decade, it has become clear that virtually all cells release different types of extracellular vesicles (EVs), which can be taken up by nearby or distant cells modulating their activity. Initially, EVs were associated to a mechanism involved in the elimination of… CONTINUE READING
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