Sigmoidal substrate saturation curves in Michaelis-Menten mechanism as an artefact.

@article{Fischer1975SigmoidalSS,
  title={Sigmoidal substrate saturation curves in Michaelis-Menten mechanism as an artefact.},
  author={Edgar Fischer and T Keleti},
  journal={Acta biochimica et biophysica; Academiae Scientiarum Hungaricae},
  year={1975},
  volume={10 3},
  pages={221-7}
}
The conditions under which sigmoidal substrate saturation curves are to be expected in the simple Michaelis-Menten mechanism and the Michaelis-Menten mechanism combined with the concomitant partial inactivation of the enzyme have been determinee solved numerically for different sets of rate constants by computer simulation on the basis of the second order… CONTINUE READING