Sigma factors and promoters in Corynebacterium glutamicum.

  title={Sigma factors and promoters in Corynebacterium glutamicum.},
  author={Miroslav P{\'a}tek and Jan Ne{\vs}vera},
  journal={Journal of biotechnology},
  volume={154 2-3},
The Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA polymerase (RNAP): primary sigma factor SigA (σ(A)), primary-like SigB and 5 other alternative sigma factors (SigC, SigD, SigE, SigH and SigM). Each sigma factor is responsible for recognizing promoters of genes belonging to a regulon (sigmulon) involved in specific functions of the cell. Most promoters of C. glutamicum housekeeping genes are recognized by RNAP+σ(A), whereas σ(B) is involved in transcription of a… CONTINUE READING
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