Sigma competition: the contest between bacteriophage T4 middle and late transcription.

@article{Kolesky1999SigmaCT,
  title={Sigma competition: the contest between bacteriophage T4 middle and late transcription.},
  author={Scott E Kolesky and Mohamed Ouhammouch and Edward N. Brody and E. Peter Geiduschek},
  journal={Journal of molecular biology},
  year={1999},
  volume={291 2},
  pages={267-81}
}
In bacterial transcription, diverse sigma-family promoter recognition proteins compete for a common RNA polymerase core. Bacteriophage T4 infection ultimately reduces this competition to a duel between activated viral middle and enhanced late transcription, involving two sigma proteins, two phage-encoded activator proteins and two phage-specific co-activators. This competition has been analyzed in vitro, and the relative abundances in T4-infected Escherichia coli of the participating proteins… CONTINUE READING

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