Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes.

@article{Zhang2000Siglec9AN,
  title={Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes.},
  author={Jiquan Zhang and Gavin Nicoll and Christopher Scott Jones and Paul R. Crocker},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 29},
  pages={22121-6}
}
Here we characterize the properties and expression pattern of Siglec-9 (sialic acid-binding Ig-like lectin-9), a new member of the Siglec subgroup of the immunoglobulin superfamily. A full-length cDNA encoding Siglec-9 was isolated from a dibutyryl cAMP-treated HL-60 cell cDNA library. Siglec-9 is predicted to contain three extracellular immunoglobulin-like domains that comprise an N-terminal V-set domain and two C2-set domains, a transmembrane region and a cytoplasmic tail containing two… CONTINUE READING
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