Siegesbeckia glabrescens attenuates allergic airway inflammation in LPS-stimulated RAW 264.7 cells and OVA induced asthma murine model.

@article{Jeon2014SiegesbeckiaGA,
  title={Siegesbeckia glabrescens attenuates allergic airway inflammation in LPS-stimulated RAW 264.7 cells and OVA induced asthma murine model.},
  author={Chan-Mi Jeon and In-sik Shin and Na-Rae Shin and Ju-Mi Hong and Ok-Kyoung Kwon and Hui-Seong Kim and Sei-Ryang Oh and Pyung-Keun Myung and K S Ahn},
  journal={International immunopharmacology},
  year={2014},
  volume={22 2},
  pages={414-9}
}
Siegesbeckia glabrescens (SG) is a plant growing in Korea that is used as a traditional medicine for various inflammatory diseases. In this study, we investigated the protective effects of SG extract on allergic asthma in an ovalbumin (OVA)-induced asthma murine model and lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Female BALB/c mice were sensitized by intraperitoneal injection of OVA on days 0 and 14 and then challenged with OVA from days 21 to 23. SG (30mg/kg) was administered by oral… CONTINUE READING
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