Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs.

@article{Joad1995SidestreamSE,
  title={Sidestream smoke effects on lung morphology and C-fibers in young guinea pigs.},
  author={Jesse P. Joad and John M Bric and Kent E. Pinkerton},
  journal={Toxicology and applied pharmacology},
  year={1995},
  volume={131 2},
  pages={289-96}
}
Children raised in homes with smokers have more frequent respiratory symptoms, decreased lung function, and increased airway reactivity. This study was designed to evaluate whether chronic exposure of developing guinea pigs to sidestream smoke (SS) would impair lung function and morphology and/or change the activity of a pulmonary defense mechanism, the local bronchopulmonary C-fiber system. Duncan-Hartley guinea pigs (n = 29) were exposed to filtered air (FA) or to SS for 6 h/day, 5 days/week… CONTINUE READING

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