Siderophores from neighboring organisms promote the growth of uncultured bacteria.

  title={Siderophores from neighboring organisms promote the growth of uncultured bacteria.},
  author={Anthony D'Onofrio and Jason M Crawford and Eric Jonathan Stewart and Kathrin Witt and Ekaterina Yu Gavrish and Slava S. Epstein and Jon Clardy and Kim Lewis},
  journal={Chemistry & biology},
  volume={17 3},
The majority of bacterial species do not grow on synthetic media. Many non-growers require growth factors from other bacteria, but the nature of these compounds is largely unknown. We show here that previously uncultured isolates from marine sediment biofilm grow on a Petri dish in the presence of cultured organisms from the same environment. The growth factors produced by one cultured helper strain were identified as new acyl-desferrioxamine siderophores. A panel of previously uncultured… CONTINUE READING
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