Side populations of gastrointestinal cancers are not enriched in stem cells.

@article{Burkert2008SidePO,
  title={Side populations of gastrointestinal cancers are not enriched in stem cells.},
  author={Julia S Burkert and William R. Otto and Nicholas Anthony Wright},
  journal={The Journal of pathology},
  year={2008},
  volume={214 5},
  pages={564-73}
}
The side population (SP) phenotype, defined as the reserpine-blockable ability to efflux the nucleic acid dye Hoechst 33342, has been claimed to be enriched for stem cells in several human normal tissues, cancers and cell lines, and thus may be useful for the identification and isolation of cancer stem cells. We demonstrated the presence of SP fractions in all of seven tested gastrointestinal cancer cell lines. Four cell lines were selected (HT29, HGT101, Caco2 and HRA19a1.1) for detailed… CONTINUE READING