Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas

@article{Murase2009SidePC,
  title={Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas},
  author={Masaki Murase and Masanobu Kano and Tomohide Tsukahara and Akiko Takahashi and Toshihiko Torigoe and Satoshi Kawaguchi and Shunsuke Kimura and Takehiko Wada and Yoshito Uchihashi and Takahisa Kondo and Toshihiko Yamashita and Noriyuki Sato},
  journal={British Journal of Cancer},
  year={2009},
  volume={101},
  pages={1425 - 1432}
}
Background:Several human cancers have been found to contain cancer stem-like cells (CSCs) having cancer-initiating ability. However, only a few reports have shown the existence of CSCs in bone and soft tissue sarcomas. In this study, we identified and characterised side population (SP) cells that showed drug-resistant features in human bone sarcoma cell lines.Methods:In seven osteosarcoma cell lines (OS2000, KIKU, NY, Huo9, HOS, U2OS and Saos2) and in one bone malignant fibrous histiocytoma… CONTINUE READING

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Antigenic peptide vaccination: Provoking immune response and clinical benefit for cancer

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