Side‐effects of henna and semi‐permanent ‘black henna’ tattoos: a full review

  title={Side‐effects of henna and semi‐permanent ‘black henna’ tattoos: a full review},
  author={Anton C de Groot},
  journal={Contact Dermatitis},
Henna, the dried and powdered leaf of Lawsonia inermis, is widely used as a dye for the skin, hair, and nails, and as an expression of body art, especially in Islamic and Hindu cultures. As it stains the skin reddish‐brown, it is also called red henna. Black henna is the combination of red henna with p‐phenylenediamine (PPD), and is used for temporary ‘black henna tattoos’. This article provides a full review of the side‐effects of topical application of red and black henna, both cutaneous… 
Hypertrichosis due to black henna tattoo treated with 755 nm Alexandrite Laser
This case is an example of localized hypertrichosis after henna tattoo and treated immediately with 755 nm Alexandrite Laser in one session.
Are henna tattoos harmless? Report of clinical cases
This work presents three cases of children with contact allergic dermatitis caused by black henna which resolved with low potency topical steroids and aims to educate contact health-care professionals to be aware of this adverse effect onblack henna.
Henna beyond skin arts: Literatures review
This review highlights pharmacological effectiveness and adverse effects of henna and different experimental in vitro studies showed many pharmacological effects of L. inermis.
Sensitization and Clinically Relevant Allergy to Hair Dyes and Clothes from Black Henna Tattoos: Do People Know the Risk? An Uncommon Serious Case and a Review of the Literature
The case of an 18-year-old girl who became clinically sensitive to textile dyes after having showed a serious reaction both to her first hair dying and following the application of a temporary henna tattoo when she was a kid is presented.
Henna stone: a lesser‐known solid material from which to obtain black henna paste
It is proposed that ‘henna stones’ contain high proportions of p-phenylenediamine, significantly higher than previously reported PPD concentrations in black henna samples.
Allergic dermatitis - Black henna (para-phenylenediamine) use among the East African patient population in a general practice setting.
A case of allergic dermatitis due to a black henna use seen in a general practice clinic setting is described and the role of education and counselling of a particular community is highlighted.
Hypersensitivity reactions due to black henna tattoos and their components: are the clinical pictures related to the immune pathomechanism?
The literature underlines that different clinical manifestations are related to black henna containing PPD, and its derivative products may cause delayed-type as well as immediate-type reactions, and further studies are needed to investigate the relationship between clinical and morphological aspects of PPD contact dermatitis and the T cell subsets predominance.
‘Sign of the kiss’ from black henna tattoos
This work describes a unique case in whom the application of black henna tattoo ink resulted in severe allergic contact dermatitis at the tattooed sites, but also in non-tattooed skin areas juxtaposed to these – a so-called ‘sign of the kiss’.
An Allergic Reaction to Henna Used in a Traditional Painting Ceremony
A 22-year-old female patient, who was born in India and immigrated to Israel, presented with itching and a raised rash on her right hand a few days after the traditional henna ceremony, which was held on the day before her wedding.
Allergic contact dermatitis caused by a new temporary blue–black tattoo dye – sensitization to genipin from jagua (Genipa americana L.) fruit extract
Temporary tattoos made with an extract of the jagua fruit (Genipa americana L.) are becoming increasingly popular. It is claimed that it is ‘dermatologically tested’ and does not contain


Henna tattooing dermatitis: consider an additive as the culprit.
  • J. Urkin,
  • Medicine
    The British journal of general practice : the journal of the Royal College of General Practitioners
  • 2006
Henna is made of the ground leaves of Lawsonia unermis or alba, mixed with water or oil, and Para-phenylenediamine (PPD), which is commercially used in hair colouring, is commonly added to henna preparations to obtain a darker shade — ‘black henna’ and to shorten the fixation time of the colour to the skin.
Acute Allergic Contact Dermatitis Due to Para‐Phenylenediamine after Temporary Henna Painting
A 17‐year‐old girl with blisters over her hands of five‐days duration that appeared within 72 hours of applying a temporary henna paint to her hands during a social occasion is reported here, with clinical diagnosis of acute allergic contact dermatitis.
Allergic contact dermatitis from temporary henna tattoo
A 9‐year‐old boy with allergic contact dermatitis due to temporary henna tattooing is reported, and patch testing showed a positive reaction to PPD, which may be a very potent contact sensitizer.
Severe inflammatory and keloidal, allergic reaction due to para-phenylenediamine in temporary tattoos.
A 22-year-old man who developed severe inflammatory and keloidal, moderately bullous allergic reaction after henna paint-on tattoo is reported, and resolution was obtained in two weeks.
Identification and quantification of para-phenylenediamine in a temporary black henna tattoo.
The presence of PPD in black henna tattoo mixtures in high concentration poses a health hazard and a risk of allergic contact sensitization with potential long-term consequences.
Quantification of para‐phenylenediamine and heavy metals in henna dye
This work examined 15 henna samples available in Korea for the presence of para‐phenylenediamine (PPD) and heavy metals such as nickel, cobalt, chromium, lead and mercury using high‐performance liquid chromatography (HPLC), atomic absorption spectroscopy (AAS), mercury analyser and inductively coupled plasma emission spectroscopic.
‘Black henna’ tattoos: an occult source of natural rubber latex allergy?
Temporary ‘black henna’ tattoos are an increasingly popular body decoration with a growing incidence of associated adverse events. We report the case of a 14 year old girl presenting with an acute
Allergic contact dermatitis to pure henna.
A case of allergic contact dermatitis from pure henna that is also used for the relief of rheumatic pain is reported.
Black henna tattoos: coexisting rubber and para‐phenylenediamine allergy?
PPD, a widely recognized potent contact sensitizer, causes severe reactions within 3 days to 4 weeks and results in black henna tattoos, which are promoted as a temporary, harmless , and fashionable body adornment among young adults and children.