Sickle cell trait-associated deaths: a case series with a review of the literature.

@article{Thogmartin2011SickleCT,
  title={Sickle cell trait-associated deaths: a case series with a review of the literature.},
  author={Jon R Thogmartin and Christopher I Wilson and Noel A Palma and Susan S Ignacio and Mark J Shuman and Lisa M Flannagan},
  journal={Journal of forensic sciences},
  year={2011},
  volume={56 5},
  pages={1352-60}
}
This study presents a series of 16 carriers of hemoglobin S (HbS) who died during various circumstances. Many of the cases were associated with mild to moderate exertion. The onset and/or duration of symptoms varied from a few minutes to several hours with many displaying a prolonged lucid interval with stable vital signs. Despite seeking medical treatment, sickle cell trait-related micro-occlusive crisis was never considered in the differential diagnosis. Several cases were associated with… CONTINUE READING