Sickle cell solutions in sight

Abstract

In 1956, researchers tracked the root cause of sickle cell disease (SCD) to a point mutation in the haemoglobin β-chain that causes the deformation of red blood cells. Sixty years on, the only disease-modifying drug approved to reduce painful and damaging events that are caused by the resulting blockage of blood vessels has limited utility. But the… (More)
DOI: 10.1038/nrd.2016.177

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