Sickle-cell haemoglobin O disease in a Sudanese family.

Abstract

Besides sickle-cell anaemia, the finding of Hb S with other /3-chain variants of adult haemoglobin was first demonstrated by Itano and Neel (1950) in the well-known discovery of sicklecell Hb C disease. Since then Hb S has been observed with Hb D, E, G, J. and K (Itano, 1951; Aksoy and Lehmann, 1957; Schwartz and Spaet, 1955 ; Went and MacIver, 1959; O… (More)

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