Sickle cell disease in pregnancy

  title={Sickle cell disease in pregnancy},
  author={Eugene Oteng-Ntim and Shazia Nazir and Tasneem Singhal and Jenna B. Howard},
Summary With advances in management, many women with sickle cell disease now survive to have children. The high risk of fetal and maternal sequelae mandates multidisciplinary management involving an obstetrician, a haematologist, an anaesthetist and a haemoglobinopathy specialist nurse. Hydroxyurea, a new treatment for sickle cell disease, is contraindicated in pregnancy. Exchange transfusion may be indicated in women with a serious obstetric or haematological complications. In those with… CONTINUE READING