Sickle cell disease: ischemia and seizures.

@article{Prengler2005SickleCD,
  title={Sickle cell disease: ischemia and seizures.},
  author={Mara Prengler and Steven G. Pavlakis and Stewart Boyd and Alan Connelly and Fernando Calamante and Wui K. Chong and Dawn Saunders and Timothy Cox and Michael Bynevelt and Roderick Lane and Aidan Laverty and Fenella Jane Kirkham},
  journal={Annals of neurology},
  year={2005},
  volume={58 2},
  pages={290-302}
}
Although the prevalence of seizures in children with sickle cell disease (SCD) is 10 times that of the general population, there are few prospectively collected data on mechanism. With transcranial Doppler and magnetic resonance imaging (MRI) and angiography, we evaluated 76 patients with sickle cell disease, 29 asymptomatic and 47 with neurological complications (seizures, stroke, transient ischemic attack, learning difficulty, headaches, or abnormal transcranial Doppler), who also underwent… CONTINUE READING

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