Siblings of Okinawan centenarians share lifelong mortality advantages.

@article{Willcox2006SiblingsOO,
  title={Siblings of Okinawan centenarians share lifelong mortality advantages.},
  author={Bradley J. Willcox and Donald Craig Willcox and Qimei He and Jess David Curb and Makoto Suzuki},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2006},
  volume={61 4},
  pages={345-54}
}
Okinawa, an isolated island prefecture of Japan, has among the highest prevalence of exceptionally long-lived individuals in the world; therefore, we hypothesized that, within this population, genes that confer a familial survival advantage might have clustered. We analyzed the pedigrees of 348 centenarian families with 1142 siblings and compared sibling survival with that of the 1890 Okinawan general population cohort. Both male and female centenarian siblings experienced approximately half… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today’s Nonagenarians

The journals of gerontology. Series A, Biological sciences and medical sciences • 2018
View 4 Excerpts
Highly Influenced

FOXO Transcriptional Factors and Long-Term Living

Oxidative medicine and cellular longevity • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 79 references

Allelic variation and human longevity.

Science of aging knowledge environment : SAGE KE • 2005
View 5 Excerpts
Highly Influenced

Life-long sustained mortality advantage of siblings of centenarians.

Proceedings of the National Academy of Sciences of the United States of America • 2002
View 4 Excerpts
Highly Influenced

A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects

AK Niemi, JS Molianen, M Tanaka
Eur J Hum Genet • 2005
View 1 Excerpt

Longevity genes: from primitive organisms to humans.

Mechanisms of ageing and development • 2005

Similar Papers

Loading similar papers…