Sialylation of lipooligosaccharides promotes biofilm formation by nontypeable Haemophilus influenzae.

@article{Swords2004SialylationOL,
  title={Sialylation of lipooligosaccharides promotes biofilm formation by nontypeable Haemophilus influenzae.},
  author={William E. Swords and Miranda L. Moore and Luciana Godzicki and Gail T Bukofzer and Michael J. Mitten and Jessica L Voncannon},
  journal={Infection and immunity},
  year={2004},
  volume={72 1},
  pages={106-13}
}
Nontypeable Haemophilus influenzae (NTHi) is a major cause of opportunistic respiratory tract infections, including otitis media and bronchitis. The persistence of NTHi in vivo is thought to involve bacterial persistence in a biofilm community. Therefore, there is a need for further definition of bacterial factors contributing to biofilm formation by NTHi. Like other bacteria inhabiting host mucosal surfaces, NTHi has on its surface a diverse array of lipooligosaccharides (LOS) that influence… CONTINUE READING

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